منابع مشابه
Shock and awe pedagogy!
id 1427007 [January 2007].7. Hubbard R, Munford S. Presence of the “Alkaline Tide”. JAMA 80: 304–305, 1923.8. Lawson DM. A model for visualizing fluid handling by the gastrointestinal tract. Adv Physiol Educ 27: 87–88, 2003.9. Lujan HL, DiCarlo SE. Physiology should be taught as science is practiced: an inquiry-based activity to investigate the “alkaline tide”. Adv Physiol Educ 39: ...
متن کاملShock and awe: unleashing the heat shock response to treat Huntington disease.
The heat shock response (HSR) is a highly conserved protective mechanism that enables cells to withstand diverse environmental stressors that disrupt protein homeostasis (proteostasis) and promote protein misfolding. It has been suggested that small-molecule drugs that elicit the HSR by activating the transcription factor heat shock factor 1 might help mitigate protein misfolding and aggregatio...
متن کاملHDAC Inhibitors and Heat Shock Proteins (Hsps)
Epigenetic alterations, including DNA acetylation, hypermethylation and hypomethylation, and the associated transcriptional changes of the affected genes are central to the evolution and progression of various human cancers, including pancreatic cancer. Cancer-associated epigenetic alterations are attractive therapeutic targets because such epigenetic alterations, unlike genetic changes, are po...
متن کاملHeat shock and the heat shock proteins.
As all biologists appreciate, there is constant interaction between life and the environment, and temperature plays a critical role. It establishes distribution limits, it affects rates of function as well as the survival of organisms. Notoriously sensitive to temperature is plant growth. Critical steps in plant life such as germination, flowering and breaking of dormancy can be manipulated by ...
متن کاملShock and Awe in the Civil Engineering Classroom
When one advocates using drama to breathe fresh life into a col lege classroom, engineering is not the first subject that comes to mind. Law, history, and political science seem much more likely candidates. Law offers a natural source of conflict and resolution as major issues are argued passionately by both sides and a jury or all-powerful judge decides the outcome; there are clear winners an...
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ژورنال
عنوان ژورنال: Science-Business eXchange
سال: 2012
ISSN: 1945-3477
DOI: 10.1038/scibx.2012.62